Tuesday, 22 June 2010

C.Difficile in pigs and people - investigation

Those of you who read me on the newsgroup “uk.business.agriculture” will know that I have long added the following to my signature :

“Release and independently audit the results of testing British pigs for MRSA and C.Diff now!”

C.Diff was added some years ago, when pretty much alone, I began to suspect that there was some connection between the rise in C.Diff deaths in British hospitals and pig production.

The details are in the newsgroup archives.

I tracked the strains and repeatedly warned that different identities were given to the same strain in different places and that the outbreaks tended to come in the same areas as intensive pig farming.

Quebec and Ontario were especially badly hit.

Anyway, once again the Dutch shine.


Netherlands: Strong increase in C. difficile in pigs 22 Jun 2010

Research at Leiden University, the Netherlands, showed that the bacteria Clostridium difficile is increasingly present in Dutch pig farms, agricultural newspaper Agrarisch Dagblad reports.

The results were obtained after tests had been carried out at the university's animal health faculty, in collaboration with the city's academic medical centre (LUMC). The increase may well be the result of strong antibiotic use in livestock.

C. difficile causes diarrhoea in piglets and was discovered in pigs for the first time in 2007 – the ribotype 078 was found at the time.

"An increase of C. difficile, ribotype 078, was also confirmed in human patients in the Netherlands, in the same timeframe," explained Ed Kuijper, medical microbiologist, LUMC.
Humans and pigs

It is being researched whether there is a link between the increase in humans and in pig production. "There is no evidence that there is a danger for people having direct contact with pigs – or that consuming pork would pose a risk," Kuijper added. He said it is difficult to trace the origins of this strain of C. difficile through epidemiological research as the bacteria has become widespread by now.

In humans, this type of Clostridium mainly occurs with people who have been consuming a lot of antibiotics, causing a balance disruption in the gastro-intestinal tract. "We suspect that in pig production, there is also a link between the use of antibiotics and the prevention of C. difficile," Kuijper said.