Saturday, 16 June 2012

Porcine Circovirus PCV2 - the facts

A useful summary of porcine circovirus and its ramifications, with more to come.

Britain was never told that the disease hit Britain's pigs in 1999, its significance to the disastrous Classical Swine Fever (CSF) and, Foot and Mouth (FMD) epidemics the following year, or the significance now to antibiotic resistance arising from antibiotic use to deal with co-infections and, of course, the subsequent spread to and by humans.

Britain did not know that the pigs catching and culled for CSF and FMD were already sick with circovirus.

It seems to have been some kind of state secret, silence enforced by the British veterinary civil service, who were also attempting to intimidate a witness to Parliament.

As so often in history, events in Britain, unknown to the British public, are unravelling abroad.

Abstract here

Vet Pathol. 2012 Jun 12. [Epub ahead of print]

Current State of Knowledge on Porcine Circovirus Type 2-Associated Lesions.


College of Veterinary Medicine, Iowa State University, Ames, Iowa.


Porcine circovirus type 2 (PCV2), a small single-stranded DNA virus, was initially discovered in 1998 and is highly prevalent in the domestic pig population. Disease manifestations associated with PCV2 include postweaning multisystemic wasting disease (PMWS), enteric disease, respiratory disease, porcine dermatitis and nephropathy syndrome (PDNS), and reproductive failure. Although these clinical manifestations involve different organ systems, there is considerable overlap in clinical expression of disease and presence of lesions between pigs and within herds. It is now widely accepted that PCV2 can be further subdivided into different types, of which PCV2a and PCV2b are present worldwide and of greatest importance. This review will focus on PCV2-associated lesions in different organ systems.


[PubMed - as supplied by publisher]